Differential diagnosis of central neuroepithelial detachment associated with optic disc pit: two clinical cases

Optic disc pit is a congenital, rare anomaly that represents a limited depression in the optic disc. A rather frequent complication of this pathology is detachment of neuroepithelium in the central zone, which occurs due to fluid infiltration into the subretinal space and causes a decrease in visual acuity. Modern methods such as optical coherence tomography and fluorescence angiography are used for diagnosis. Treatment of this pathology is only surgical and all known methods are aimed at stopping the seepage of fluid from the optic disc pit. It is also necessary to perform differential diagnostics of central detachment of neuroepithelium associated with optic disc pit. Purpose. To demonstrate an approach to the differential diagnosis of central detachment of neuroepithelium associated with optic disc pit on the basis of two clinical cases. Material and methods. This article presents two clinical cases: neuroepithelial detachment associated with optic disc pit and chronic central serous chorioretinopathy. Results and discussion. Comparison of the two clinical cases revealed similarities in ophthalmoscopic pattern and differences on OCT and FAG images. Conclusion. Fluid accumulation under neuroepithelium is not a pathognomonic sign, therefore it is important to perform differential diagnosis in central serous retinal detachment associated with optic disc pit.