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March 19, 2024JACC Case ReportsOpen Access

Successful Balloon-Expandable Transcatheter Aortic Valve Replacement for Extremely Large Annulus (>1,000 mm2)

Tadatomo Fukushima Kenichi Ishizu Akihiro Isotani Shinichi Shirai Kenji Andò

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Abstract

Transcatheter aortic valve replacement in extra-large annulus is challenging because of the limited sizes and data of the current commercial prosthesis sizes available. We present a case of successful transcatheter aortic valve replacement with a new balloon-expandable SAPIEN 3 Ultra RESILIA valve for an aortic annulus area >1,000 mm

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Fukushima et al. (2024) studied this question.

synapsesocial.com/papers/68e73752b6db6435876b05d1 https://doi.org/10.1016/j.jaccas.2024.102302

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Overexpansion of the SAPIEN 3 Transcatheter Heart Valve in a Tricuspid Aortic Valve with Huge Annuluscase_report · 2021
2Transcatheter Aortic Valve Implantation in a Massive Aortic Annulus With a Novel Balloon-Expandable Valvecase_report · 2026
3TAVR in an XXXL annulus (1057 mm<sup>2</sup>) with type I bicuspid aortic valvecase_report · 2022 · 1 citations
4Transcatheter aortic valve implantation in large and extra-large aortic annuli: Contemporary evidence and performance of third-generation devicesreview · 2025
5Clinical Outcomes of Transcatheter Aortic Valve Implantation in Patients With Extremely Large Annulus and SAPIEN 3 Dimensions Based on Post-Procedural Computed Tomographycohort · 2019 · 20 citations

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Worldwide experience with the 29-mm Edwards SAPIEN XTTM transcatheter heart valve in patients with large aortic annulus2012
Performance of XL Sizes of Myval Balloon-Expandable Valve in Real-World Patients with Extremely Large Aortic Annuli2026
P203. Transcatheter versus Surgical Aortic Valve Replacement in Large and Extra-Large Aortic Annuli2026

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