Key result
TAVI using Myval valve balloon overfilling appears feasible for massive aortic annuli exceeding 1,000 mm2.
Why the study?
TAVI can be performed off-label in patients with a massive aortic annulus using smaller valves with additional volume, but this carries risks such as paravalvular leak and valve embolism.
Case Report (n=1)
A novel 35-mm balloon-expandable valve (Myval) with balloon overfilling offers a potential solution for TAVI in patients with a massive aortic annulus, avoiding the risks of over-expanding smaller valves.
May enable TAVI for massive aortic annuli; extends balloon-expandable valve applications but needs further study.
CASE SUMMARY: ) using a novel 35-mm balloon-expandable valve. TAVI can be performed off-label in selected patients with a massive aortic annulus using commercially available 29-mm transcatheter aortic valves by adding additional volume; however, this risks paravalvular leak, valve embolism, and damage to bioprosthetic leaflets. TAKE-HOME MESSAGE: using Myval 35-mm balloon-expandable valve with balloon overfilling.
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Al-Shaibi et al. (2026) conducted a case report in Massive aortic annulus requiring TAVI (n=1). Myval 35-mm balloon-expandable valve with balloon overfilling was evaluated. Transcatheter aortic valve implantation was successfully performed in a patient with a massive aortic annulus using a novel Myval 35-mm balloon-expandable valve with balloon overfilling.
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