A photo‐induced Minisci–type cyanoalkylation of azauracils was developed under metal‐free and base‐free conditions. Readily available cyclobutanone oxime esters were used as the cyanoalkylating reagents via C−C bond cleavage to generate the γ‐cyanoalkyl azauracil derivatives in good to moderate yields. The introduced cyano group can be easily converted into many other functional groups, thus makes current protocol more practical.
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Xiang et al. (2024) studied this question.
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