Case Report and Literature ReviewBackground: There are only rare case reports that revealed the efavirenz (EFV) toxicity.Case Report: This study presents an acute intoxication with 12 g of efavirenz in a 16-yearold healthy girl whose main problem was dose-dependent neurotoxicity.No other serious EFV-related side effects were seen.Previous serious side effects of EFV were observed in HIV-infected patients who underwent long-term combination drug therapy. Conclusion:Accordingly, in terms of the key clinical messages, serious adverse effects of efavirenz are expected to be observed in long-term use in combination with other antiretroviral drugs.
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Moghimi et al. (2024) studied this question.
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