⌘+K

Pulse Explore Communities Researchers Journals

Browser extensionInstagram

Home Communities Explore

March 16, 2024Epilepsy ResearchOpen Access

Lacosamide extended-release capsules are bioequivalent to lacosamide immediate-release tablets: Pharmacokinetic observations and simulations

James W. Wheless Barry E. Gidal Lixin Gong Shaoqiong Lyu Xun Zheng Rong Li Wilson J. Chang Marie Tan

View Full Paper

Ask AI

Bookmark

Share

Ask about this paper

Answers are grounded in this paper and cite their sources.

Ask your own question…

Abstract

Assess the bioequivalence of lacosamide extended-release (XR) capsules and immediate-release (IR) tablets and answer real-world clinical questions regarding the use of lacosamide XR.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Wheless et al. (2024) studied this question.

synapsesocial.com/papers/68e73ba2b6db6435876b599c https://doi.org/10.1016/j.eplepsyres.2024.107350

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 10 related papers. Consider them for comparative context:

1Cardiac safety of lacosamide: the non-clinical perspectivepreclinical · 2015 · 12 citations
2Development and validation of a population pharmacokinetic model for lacosamide in adult patients with epilepsy to inform precision dosingOriginal Research · 2026 · 3 citations
3Lacosamide cardiac safety: a thorough QT/QTc trial in healthy volunteersRCT · 2015 · 29 citations
4Comparison of lacosamide concentrations in cerebrospinal fluid and serum in patients with epilepsyOriginal Research · 2015 · 31 citations
5Lacosamide in Migraine: Mechanistic Insights and Emerging Clinical EvidenceOriginal Research · 2026
6Evaluating Lacosamide in the management of focal Seizures: A narrative review of Efficacy, safety and Tolerability2025 · 1 citations
7Long-term efficacy, safety, and tolerability, including behavior and executive functioning, during adjunctive lacosamide treatment in pediatric patients with uncontrolled epilepsy2024 · 2 citations
8Intravenous push lacosamide: Successful implementation and patient outcomes across a health system2024 · 1 citations
9Hyperphosphorylated tau pathology in patients with epilepsy and dementia – Neuropathological insights from a historical autopsy cohortEpilepsy Research · 2026
10Corpus callosotomy in Lennox-Gastaut syndrome: Effectiveness, safety, and predictors of outcome: A systematic review and meta-analysisEpilepsy Research · 2026

More from Epilepsy Research

More from University of Wisconsin–Madison

More from Le Bonheur Children's Hospital