Aseptic meningitis (AM) is a condition of meningeal irritation evidenced by headache, nuchal rigidity, and cerebrospinal fluid (CSF) changes in the absence of viral, bacterial, fungal, or autoimmune causes. Diagnosis is usually made by cessation of the suspected drug followed by resolution of symptoms and normalization of CSF cell counts in 48 to 72 hours. With prompt diagnosis and discontinuation of the offending drug, complete recovery is expected [4,5]. We present a case of an immunocompetent 14-year-old female who developed AM following treatment with Trimethoprim/Sulfamethoxazole (TMPSMX).
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Johnson-Barlow et al. (2024) studied this question.
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