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March 13, 2024British Journal of Haematology

Refining risk stratification in paediatric B‐acute lymphoblastic leukaemia: Combining IKZF1plus and Day 15 MRD positivity

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Authors

HLHsi‐Che LiuMackay Memorial HospitalYHYing‐Jung HuangChang Gung Memorial HospitalTJTang‐Her JaingChang Gung University

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Liu et al. (2024) studied this question.

synapsesocial.com/papers/68e74345b6db6435876bc5eahttps://doi.org/10.1111/bjh.19338
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1IKZF1 plus Defines a New Minimal Residual Disease–Dependent Very-Poor Prognostic Profile in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia2018 · 310 citations
  2. 2The clinical impact of IKZF 1 deletions in paediatric B‐cell precursor acute lymphoblastic leukaemia is independent of minimal residual disease stratification in Nordic Society for Paediatric Haematology and Oncology treatment protocols used between 1992 and 20132015 · 51 citations
  3. 3Ikaros (IKZF1) alterations and minimal residual disease at day 15 assessed by flow cytometry predict prognosis of childhood BCR/ABL‐negative acute lymphoblastic leukemia2012 · 28 citations
  4. 4Prognostic impact of IKZF1 deletions in association with vincristine–dexamethasone pulses during maintenance treatment of childhood acute lymphoblastic leukemia on trial ALL-BFM 952017 · 28 citations
  5. 5IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol2012 · 168 citations