We present a method for the synthesis of substituted indolo[1,2‐ a ]quinoline‐5(6 H )‐ones starting from 1‐(2‐ethynylphenyl)‐1 H ‐indoles. The transformation involves gold‐catalyzed oxidation of the triple bond followed by acid‐promoted intramolecular cyclization at the indole C2 position. Demonstrating noteworthy versatility, the reaction tolerates a wide array of substituents on the indole core and proceeds in good to excellent yields (up to 93 %).
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Brambilla et al. (2024) studied this question.
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