⌘+K

Pulse Explore Clubs Researchers Journals

Home Clubs Explore

March 11, 2024Immunopharmacology and Immunotoxicology

Isorhamnetin ameliorates cisplatin-induced acute kidney injury in mice by activating SLPI-mediated anti-inflammatory effect in macrophage

Jian Jia Yuqing Li Han Rang-Yue Xia Zhong Ke-huan Xie Ying Yan Li Wang Ruizhi Tan

View Full Paper

Ask AI

Bookmark

Share

Abstract

Isorhamnetin (IH) has been reported to have significant anti-inflammatory effects in various diseases, but its role and mechanism in AKI remain unclear. This study aimed to explore the potential role and mechanism of isorhamnetin in inhibiting macrophage related inflammation and improving AKI injury.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Jia et al. (2024) studied this question.

synapsesocial.com/papers/68e74801b6db6435876c15cc https://doi.org/10.1080/08923973.2024.2329621

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Isorhamnetin attenuates diabetic kidney disease by modulating mitochondrial homeostasis and suppressing cGAS-STING axis-dependent NLRP3 inflammasome activationOriginal Research · 2026 · 1 citations
2Mitigation of cisplatin-induced cardiotoxicity by Isorhamnetin: Mechanistic insights into oxidative stress, inflammation, and apoptosis modulation2024 · 27 citations
3Isorhamnetin: a flavonoid, attenuated doxorubicin-induced testicular injury via regulation of steroidogenic enzymes and apoptotic signaling gene expression in male ratspreclinical · 2022 · 22 citations
4Isorhamnetin improves diabetes-induced erectile dysfunction in rats through activation of the PI3K/AKT/eNOS signaling pathway2024 · 30 citations
5Impact of isorhamnetin for suppression of electrical and structural remodeling via CaMKII-RyR2 and TRPC-mediated MAPK pathways in atrial fibrillationpreclinical · 2022