Idiopathic scrotal calcinosis: Is the cause still unknown? A case report

Idiopathic Scrotal Calcinosis (ISC) is a rare and benign dermatological condition, characterized by the formation of calcified nodules on the scrotal skin. A 47-year-old man with a 15-year history of painless, chamois-colored nodules on his scrotum. Surgical excision of the affected skin was performed, followed by primary closure, with histopathological examination confirming ISC. The patient recovered well with no recurrence noted at a 14-month follow-up. The etiology of ISC remains uncertain, with theories ranging from dystrophic calcification of epidermal cysts to Dartos muscle degeneration. In this case, no signs of epithelial cells or anatomical structure degeneration were observed, supporting the idiopathic nature of ISC. Treatment is typically surgical and aimed at aesthetic or symptomatic relief. While surgery is generally effective, the literature indicates a variable risk of recurrence, underscoring the need for long-term follow-up. This report contributes to the understanding of ISC, highlighting its idiopathic nature and the diversity of its etiological theories. It reinforces the effectiveness of surgical treatment for symptomatic relief and underscores the importance of ongoing research to elucidate the condition's etiology and optimize patient care.