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March 8, 2024Current Trends in Biotechnology and PharmacyOpen Access

Cymbopogon citratus Leaf Extract Mitigates Hepatorenal Injury in Carbon Tetrachloride and Rifampicin-Exposed Rats

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Authors

TOTemidayo Ogunmoyole

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Overview

Experimental study reveals Cymbopogon citratus leaf extract mitigates hepatorenal injury in chemically exposed rats, suggesting therapeutic potential against toxic damage.

Key Points

  • Cymbopogon citratus leaf extract mitigates toxicant-induced liver and kidney injury by reducing elevated aspartate aminotransferase and alanine aminotransferase.
  • Experimental evaluation in forty male albino rats tested carbon tetrachloride at 3 ml/kg and rifampicin at 250 mg/kg alongside silymarin as a reference drug.
  • Highlights potential therapeutic application of Cymbopogon citratus for hepatorenal injury, though this rat model requires further preclinical validation.

Cite This Study

Temidayo Ogunmoyole (2024) studied this question.

synapsesocial.com/papers/68e7541bb6db6435876cbcc2https://doi.org/10.5530/ctbp.2024.1.4
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Reversal of Chemical Potentiated Multiple End Organ Injuries by Citrus reticulata Leaf Extract2025
  2. 2Hepatoprotective Effect of Ethanolic Extract of Cnestis ferruginea Roots on Carbon tetrachloride-Induced Liver Damage in Male Rats2024
  3. 3Assessment of hepatoprotective activity of coded plant (222) leaf ethanolic extract against carbon tetrachloride-induced hepatotoxicity in Wistar rats – Part IV2017
  4. 4A comparative effects of <i>Cymbopogon citratus</i> extract on the biochemical and haematological parameters of Wistar rat2025
  5. 5Testicular pathology in albino rats administered graded doses of ethanol leaf extract of Cymbopogon citratus2024 · 1 citations