March 7, 2024American Journal of Neuroradiology

Hemorrhage Volume Drives Early Brain Injury and Outcome in Poor-Grade Aneurysmal SAH

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Authors

PPPietro PanniVita-Salute San Raffaele University FSFranco SimionatoVita-Salute San Raffaele University RCRoberta CaoHôpital Pierre Wertheimer

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Implication

Registry analysis demonstrates hemorrhage volume predicts edema and mortality in poor-grade aneurysmal subarachnoid hemorrhage, highlighting bleeding extent as a critical prognostic determinant.

Key Points

Global intracranial hemorrhage volume independently drives early brain injury, while promoting severe global cerebral edema and raising acute in-hospital mortality across poor-grade patients.
Severe global cerebral edema occurred in 54.5% of cases, and higher hemorrhage volume increased mortality risk with an adjusted odds ratio of 1.006.
Retrospective evaluation of registry records highlights bleeding volume as a vital predictor of early brain injury, though advancing age attenuates its impact on global cerebral edema.

Cite This Study

Panni et al. (2024) studied this question.

synapsesocial.com/papers/68e75433b6db6435876cc436 https://doi.org/10.3174/ajnr.a8135

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Implication

Registry analysis demonstrates hemorrhage volume predicts edema and mortality in poor-grade aneurysmal subarachnoid hemorrhage, highlighting bleeding extent as a critical prognostic determinant.

Hemorrhage Volume Drives Early Brain Injury and Outcome in Poor-Grade Aneurysmal SAH

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Key Points

Cite This Study

Hemorrhage Volume Drives Early Brain Injury and Outcome in Poor-Grade Aneurysmal SAH

Discussion

Member takes

Implication

Key Points

Cite This Study

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