The Lipidosis Profiling and C-Reactive Protein Evaluated in Patients with Prostate Cancer Attending Madonna University Teaching Hospital in Elele

One prevalent malignant tumor of the male prostate epithelium is called prostate cancer (PCa). The purpose of this study is to assess the C-reactive protein (CRP) and lipid profile of patients with PCa at Madonna University Teaching Hospital (MUTH), Elele. For the study, 50 hospital patients were enlisted. 20 of them were control patients, meaning they were not PCa patients, and the remaining 30 were patients with PCa and ranged in age from 25–65. All those engaged provided their informed permission and ethical clearance properly. Venipuncture was used to get blood samples. Enzyme-linked immunosorbent assay (ELISA) was used to analyze CRP, while total cholesterol (TCH), triglycerides (TG), high-density lipoprotein (HDL), and low-density lipoprotein (LDL) were measured using an enzymatic spectrophotometric approach. Data obtained from this study was analyzed using Statistical Package for Social Sciences (SPSS) version 21 for Windows 7 and one-way analysis of variance (ANOVA), which were used to compare the means. The results were expressed as mean ± SD and values were considered significant at p < 0.05 and non-significant at p > 0.05. Results from this study showed a significant difference (p < 0.05) in the mean values of the following: TCH levels in PCa patients (6.39 ± 0.90 mmol/L) when compared to the control group (4.10 ± 0.50 mmol/L), TG levels in PCa patients (1.84 ± 0.27mmol/L) when compared with the control group (1.26 ± 0.24 mmol/L), HDL levels in PCa patients (0.92 ± 0.10 mmol/L) when compared with the control group (1.02 ± 0.11 mmol/L), LDL levels in PCa patients (4.45 ± 1.00 mmol/L) when compared with the control group (2.33 ± 0.38 mmol/L) and CRP levels in PCa patients (4.48 ± 0.77 mg/L) when compared with the control group (3.44 ± 0.80 mg/L). This probably indicates that the PCa group developed biochemical alteration in lipid profile and CRP parameters within an increased period of time.