An Uncommon Progression of a Common AIDS-Defining Diagnosis: Metastatic Kaposi Sarcoma to Lung and Bone

AIDS-associated Kaposi sarcoma (KS) is an aggressive human herpesvirus 8–induced vascular tumor that presents as violaceous lesions on the skin or mucosal membranes. Although less common, extracutaneous metastasis of KS can involve the gastrointestinal tract, lungs, and lymph nodes. Here, we present a rare case of a newly diagnosed patient with HIV with typical KS of the gums and was found to have metastasis to the lung and ilium. This case highlights a rare presentation of an AIDS-defining disease and the importance of early diagnosis and metastatic screening.