Background: Liver resection, a crucial surgical intervention for hepatic conditions, involves removing a portion of the liver, addressing benign and malignant lesions. The Pringle's maneuver, an intermittent portal inow control, is frequently used perioperatively during liver resection. To assess whether Pringles maneuver during Aim: liver resection as a method of inow control has any inuence on operative outcome. Between July 2013 and March 2015, 80 liver resection Patients and Methods cases were randomly divided into Group A (Pringle's maneuver) and Group B (Non-Pringle's). Both groups received selective low CVP anesthesia. After excluding 14 cases, the remaining 66 cases underwent minor or major hepatectomy (≥3 segments). Assessments included blood lactate, Neutrophil-to-Lymphocyte Ratio, liver enzymes tests, and bilirubin levels on days 1, 3, and 5. Results: In Group A, major and right hepatectomies showed increased blood loss, higher transfusion needs, and prolonged hospital stays. Elevated liver enzymes, lactate levels, and Neutrophil-to-Lymphocyte ratio on day one was observed in Group A. Group A experienced signicantly higher-Grade B & C liver failure, postoperative hyperglycaemia, and mortality (ve deaths attributed to liver failure). Univariate analysis revealed age, comorbidity, liver condition, resection type, bloodless procedure, duration, N/L ratio, lactate level, and 50-50 criteria signicantly correlated with morbidity and mortality (p<0.05). Pringle's manoeuvre in liver resection extends hospital stay, heightens transfus Conclusion: ion requirement, and raises complications, particularly in diseased livers. Elevated blood lactate and Neutrophil-to-Lymphocyte ratio reliably predict postoperative liver failure and mortality.
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Sathiyamoorthy et al. (2024) studied this question.
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