Introduction: Papillary Carcinoma originating from thyroglossal duct cyst (TGDC) is very rare, occurring in less than one percent of cases. The diagnosis is often made in these situations following the removal of benign TGDC.We provide a case report that details a case of a thirty-years man who had Sistrunk's surgery for TGDC and was subsequently diagnosed to have Papillary Cancer.It is debatable how to handle these cases; the options include either a periodic monitoring following Sistrunk's Procedure or Complete thyroid gland excision +/- radio-active iodine (RAI) ablation and suppresive hormonal therapy. A th Case Presentation: irty-years man came to our OPD with anterior midline neck swelling which moved upward with deglutition and tongue protrusion.On radiology,distinct cystic lesion was seen. Sistrunk's Procedure was performed and tissue was sent for histo-pathological reporting. A papillary carcinoma foci was identied in the TGDC by histo-pathology. As a follow up and completion treatment, our patient was subjected to complete thyroidectomy. The most Discussion: frequent anomalies are TGDC which are encountered in thyroid development. Within TGDC remains, malignancy is present in one to two percent of cases with most being Papillary Carcinoma. TGDC are most common in females with ratio being 3:2.
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Mohite et al. (2024) studied this question.
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