Introduction Diabetes is one of the largest global health emergencies of this century, ranking among the 10 leading causes of mortality with Prevalence of 9.3%. Testosterone is key male sex hormone that plays an important role in the development and maintenance of secondary sexual characteristics. This study aimed to compare serum testosterone levels in diabetic and non-diabetic males and compare the relationship between serum testosterone levels and various metabolic parameters. Materials & Methods A cross sectional study conducted at our hospital for 18 months. Atotal of 200 males (100 diabetic & 100 non-diabetic) visiting the medicine OPD were included. Blood samples were collected to measure serum testosterone levels and metabolic parameters were measured using standard methods. Data was analyzed using appropriate inferential statistics, independent t-tests. Results The mean age of diabetics was 52.14years and non-diabetics were 52.61years. The results showed signicant difference in serum testosterone levels between the diabetics and non-diabetics, with the diabetics having lower levels. Additionally, it revealed negative correlations between age, BMI, WHR, FBS and total cholesterol with serum testosterone. Age, WHR, FBS and total cholesterol were statistically signicant, whereas BMI was statistically not signicant. However, creatinine showed positive correlation but was statically nonsignicant. Conclusion The serum testosterone levels were low in diabetic people when compared to non-diabetics. The metabolic parameters like Age, WHR, FBS and Total Cholesterol showed negative correlation with serum testosterone levels.
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Arora et al. (2024) studied this question.
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