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The highly potent antipsychotic haloperidole is used as third-line treatment for childhood schizophrenia, Tourette's syndrome as well as severe behavioral symptoms in children and adolescents with autism spectrum disorders or mental retardation. Aim of the study was to investigate the relationship between haloperidole dose and serum concentration as well as to generate information about a possible age-specific therapeutic reference range (TRR) in pediatric patients.
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Jung et al. (2024) studied this question.
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