Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
February 26, 2024Open Access

Dissecting the role of CAR signaling architectures on T cell activation and persistence using pooled screening and single-cell sequencing

View Full Paper
Ask AI
Bookmark
Share

Authors

RCRocío Castellanos-RuedaKWKai-Ling K. WangJFJuliette L. Forster

Discussion

Loading...

Member takes

Overview

Key Points

Key points are not available for this paper at this time.

Cite This Study

Castellanos-Rueda et al. (2024) studied this question.

synapsesocial.com/papers/68e778dab6db6435876ed8d1https://doi.org/10.1101/2024.02.26.582129
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Library-based single-cell analysis of CAR signaling reveals drivers of<i>in vivo</i>persistence2024 · 2 citations
  2. 2Recent advances on CAR-T signaling pave the way for prolonged persistence and new modalities in clinic2024 · 36 citations
  3. 3Discordant CAR-T cell signaling: implications of divergence from physiological T cell activation2025 · 7 citations
  4. 4Fully equipped CARs to address tumor heterogeneity, enhance safety, and improve the functionality of cellular immunotherapies2024 · 14 citations
  5. 5High-throughput single-cell screening of a cross-lineage CAR library for early-stage CAR design and candidate discovery2026