October 9, 2025CancersOpen Access

“Are You Just Looking to ‘Survive’?”: A Qualitative Study of Importance of Oncology Endpoints Beyond Overall Survival in Early-Stage Cancer

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Qualitative analysis reveals the significance of endpoints like recurrence-free survival in early-stage cancer, emphasizing patient perspectives.

Participants in the study valued overall survival, but many also regarded non-overall survival endpoints as crucial for their treatment goals.
Most participants felt that access to timely treatments tied to improvements in non-overall survival endpoints was essential for quality of life.
Differences in the importance of being disease-free versus longevity were noted based on individual prognosis and cancer type.
Reflexive thematic analysis helped uncover patient perspectives on treatment priorities and their alignment with clinical trial endpoints.

Szabo et al. (2025) studied this question.

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Qualitative analysis reveals the significance of endpoints like recurrence-free survival in early-stage cancer, emphasizing patient perspectives.