A randomized controlled trial comparing pioglitazone and metformin prior to In vitro fertilization in polycystic ovary syndrome -Associated infertile women: impact on pregnancy rates

Polycystic ovarian syndrome (PCOS) is one of the significant causes of infertility. Impaired glucose metabolism and insulin resistance add chiefly to the pathogenesis of PCOS. This study aimed to evaluate the efficacy of metformin and pioglitazone (insulin sensitizers) on the quality of the ovum and pregnancy rate in the IVF cycle.