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February 21, 2024Biochemistry and Biophysics ReportsOpen Access

Escherichia coli K88 activates NLRP3 inflammasome-mediated pyroptosis in vitro and in vivo

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Abstract

Pyroptosis induced by lipopolysaccharide (LPS) has an obvious impact on intestinal inflammation and immune regulation. Enterotoxigenic

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Cite This Study

Cheng et al. (2024) studied this question.

synapsesocial.com/papers/68e7833ab6db6435876f63af https://doi.org/10.1016/j.bbrep.2024.101665

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Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

1Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 InflammasomeOriginal Research · 2018 · 186 citations
2CBP22, a Novel Bacteriocin Isolated from Clostridium butyricum ZJU‐F1, Protects against LPS‐Induced Intestinal Injury through Maintaining the Tight Junction ComplexOriginal Research · 2021 · 29 citations
3Spontaneous formation of IpaB ion channels in host cell membranes reveals how Shigella induces pyroptosis in macrophagesOriginal Research · 2012 · 82 citations
4Giardia duodenalis and Its Secreted PPIB Trigger Inflammasome Activation and Pyroptosis in Macrophages through TLR4-Induced ROS Signaling and A20-Mediated NLRP3 DeubiquitinationOriginal Research · 2021 · 40 citations