Abstract No. 98 Outcomes of Prostate Artery Embolization Following Failure of Prostatic Urethral Lift (UroLift): A Case-Control Study

To compare outcomes of men undergoing prostate artery embolization (PAE) for return of lower urinary tract symptoms (LUTS) following failure of UroLift with a contemporaneous control group of men with benign prostatic hyperplasia and LUTS undergoing PAE as an index procedure. Over a four-year period, a prospectively maintained database identified 17 PAEs performed in men a mean of 48.4 months (range 33-93) following UroLift. These cases were compared to a contemporaneous control group of 49 men with prostate volumes < 100 g who underwent PAE; a 100 g threshold was utilized as these men would otherwise have been ineligible for UroLift themselves. International Prostate Symptom Severity (IPSS) scores were compared with the Mann-Whitney U test. Mean age of the UroLift cases was 67.0 years (range 57–82) and 67.6 years (range 54–83 years) among the controls (p=0.83). At baseline, mean prostate volume was 81 g among the prostatic lift patients and 70 g among controls (p=0.45). Mean IPSS baseline scores were 24.0 (range 15-32) among prostatic lift patients prior to PAE and 22.4 (range 8-34) among controls (p= 0.51). Post-intervention IPSS scores were collected at a mean of 3.1 months (range 0.33-5 months) following PAE for the UroLift patients and 4.0 (range 0.23-29 months) months for the control patients (p=0.36). Mean IPSS reduction following PAE was -14.4 (range -26-2) among UroLift patients and -11.3 (range -28-9) among controls (p=0.35). Men with prior failure of UroLift experienced similar improvements in LUTS as men with no prior prostatic intervention.