Abstract No. 226 Age of Kidney Transplant and Risk of Bleeding Following Transplant Renal Biopsy: A Single-Center Experience

To determine the risk of bleeding complications requiring intervention after transplant renal biopsy as a function of age of transplanted kidney at time of procedure. A total of 1017 patients who underwent ultrasound or CT-guided transplant kidney biopsy at a single institution over a 4-year period (2019-2023) were retrospectively identified. Demographic and clinical data were collected, including age of kidney transplant at the time of biopsy, number of cores sampled, operator, and bleeding complications. Differences in clinical and demographic data among patients with and without complications were analyzed. Of 1017 patients, 233 had a biopsy in a transplant ≤ 3 months post-transplant and 784 had a biopsy in a transplant > 3 months. Ten (0.99%) experienced bleeding complications post-biopsy that required secondary intervention. Of these patients, 8 (80%) had a kidney transplant ≤ 3 months and 2 (20%) had a kidney transplant > 3 months. Patients with a kidney transplant ≤ 3 months were 16 times more likely to experience bleeding complications requiring intervention (p < 0.001) than patients with kidney transplant > 3 months (odds ratio [OR], 0.061). Twenty-four patients developed hematoma formation post-procedure not requiring intervention, 9 with a kidney transplant ≤ 3 months (3.9%) and 15 with a kidney transplant > 3 months (1.9%). Age of renal transplant was not predictive of bleeding not requiring intervention (p = 0.08). Results are shown in Table 226.1. Patients undergoing transplant renal biopsy who have a transplanted kidney ≤ 3 months are at a significantly higher risk for bleeding complications requiring secondary intervention post-biopsy.