February 20, 2024Exploration of Targeted Anti-tumor TherapyOpen Access

The oncogenic role of hepatitis B virus X gene in hepatocarcinogenesis: recent updates

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Hepatitis B virus X protein accelerates hepatocarcinogenesis by disrupting cell cycle regulation, impairing autophagy pathways, and inhibiting programmed apoptosis.
Narrative synthesis of recent evidence indicates that HBx shifts intracellular localization to modulate transcription factors and interact with non-coding RNAs.
Highlights how dissecting the multifactorial regulatory roles of HBx across viral phases may clarify pathogenesis and uncover markers for hepatocellular carcinoma.

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Implication

Review reveals how hepatitis B virus X protein disrupts cellular pathways in chronic hepatitis B infection, highlighting critical molecular drivers of hepatocarcinogenesis.

Cite This Study

Agustiningsih et al. (2024) studied this question.

synapsesocial.com/papers/68e785bab6db6435876f85b9 https://doi.org/10.37349/etat.2024.00209

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Implication

Review reveals how hepatitis B virus X protein disrupts cellular pathways in chronic hepatitis B infection, highlighting critical molecular drivers of hepatocarcinogenesis.

The oncogenic role of hepatitis B virus X gene in hepatocarcinogenesis: recent updates

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Implication

Cite This Study

The oncogenic role of hepatitis B virus X gene in hepatocarcinogenesis: recent updates

Key Points

Discussion

Implication

Cite This Study

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