The trifluoromethylsulfinylation reaction of activated arenes with trifluoromethanesulfinyl chloride (CF 3 SOCl) in the presence of Lewis acid was achieved under mild and solvent‐free conditions. A series of aryl trifluoromethyl sulfoxides were obtained in moderate to high yields. The protocol could be extended to the perfluoroalkylsulfinylation of activated arenes, as well as the trifluoromethylsulfinylation of indoles without additive.
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Zhong et al. (2024) studied this question.
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