Serum iron and ferritin levels in female patients with gingivitis and periodontitis

Aim The aim of the study was to compare serum ferritin and iron levels and periodontal status in pre‐ and post‐menopausal female patients. Materials and Methods A total of 108 systemically healthy patients were included in the study, 63 patients in the pre‐menopause group and 45 patients in the post‐menopause group. The periodontal diagnosis was made according to the new periodontal disease classification of the American Academy of Periodontology and the European Federation of Periodontology Serum Iron (μg/dL) and Serum Ferritin (ng/mL) values were analysed in patients divided into groups according to menopausal status and periodontal status. Result The mean ferritin in pre‐menopausal women (34.96 ± 27.87 ng/mL) was lower than the mean ferritin in post‐menopausal women (64.24 ± 36.05 ng/mL), and this difference was found to be statistically significant ( P <0.001). There was no statistically significant difference between the averages of iron and ferritin according to periodontal diagnosis in pre‐menopausal women ( P = 0.200 and P = 0.858). A statistically significant difference was found between serum ferritin averages according to periodontal diagnosis in post‐menopausal women ( P < 0.001). Serum ferritin at % Interdental bone loss = 0 in Post‐M was 33.93 ± 8.65 ng/mL; 47.51 ± 16.17 ng/mL in Stage 1 periodontitis; 72.66 ± 18.12 ng/mL in Stage 2 periodontitis; It was found to be 87.4 ± 47.1 ng/mL in Stage 3–4 periodontitis. Conclusion Serum ferritin values might vary depending on the presence or severity of periodontitis in post‐menopausal women.