Transition–metal catalyzed tandem asymmetric reactions were powerful tools to access various chiral compounds. Many strategies have been developed for the coupling of 1,n‐dienes with aryl halides via a tandem Heck/Tsuji–Trost process. However, the control of regio‐ and stereo‐chemistry remains a challenging task. This minireview details the recent advances in the field of asymmetric Heck/Tsuji–Trost reactions catalyzed by palladium complex, which have opened new opportunities and expanded our understanding in this area of research in recent years.
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Zhao et al. (2024) studied this question.
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