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October 9, 2025Frontiers in ImmunologyOpen Access

Metabolic regulation of interferon-mediated innate antiviral immunity

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Viral infections disrupt metabolic pathways, affecting the host's antiviral immunity and interferon production.
Pathogens like influenza and coronaviruses can lead to severe health threats, particularly in vulnerable populations.
Understanding metabolic reprogramming may reveal new strategies for diagnosing and treating respiratory viral diseases.
This review focuses on the interplay between metabolism and innate immunity, emphasizing potential clinical applications.

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This review highlights how metabolic regulation impacts interferon-mediated antiviral immunity in infections, suggesting new treatment strategies.

Tian et al. (2025) studied this question.

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This review highlights how metabolic regulation impacts interferon-mediated antiviral immunity in infections, suggesting new treatment strategies.