Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 9, 2025Endocrinology Diabetes & MetabolismOpen Access

Remnant Cholesterol and Cardiovascular Risk in Adults With Type 1 Diabetes: A Nested Case–Control Study

View Full Paper
Ask AI
Bookmark
Share

Authors

FSFernando Sebastián‐VallesIHIñigo Hernando‐AldayLLLuis Eduardo Lander Lobariñas

Discussion

Loading...

Member takes

Overview

Nested case–control study finds elevated remnant cholesterol raises cardiovascular disease risk, suggesting crucial lipid management.

Key Points

  • Elevated remnant cholesterol is independently linked to a higher risk of cardiovascular disease in adults with type 1 diabetes.
  • Individuals with remnant cholesterol levels in the highest quartile showed an odds ratio of 4.50 for cardiovascular disease.
  • The analysis was conducted using a nested case–control design within a multicentre cohort of adults with type 1 diabetes.
  • These findings underline the necessity for targeted lipid-lowering strategies to achieve LDL-C treatment goals in individuals with type 1 diabetes.

Cite This Study

Sebastián‐Valles et al. (2025) studied this question.

synapsesocial.com/papers/68e7ba40ccde5f1021f64ca0https://doi.org/10.1002/edm2.70114
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Remnant Cholesterol: From Pathophysiology to Clinical Implications in Type 1 Diabetes2025 · 5 citations
  2. 2465-P: Distribution of Remnant Cholesterol in Patients with Type 2 Diabetes and in Nondiabetic Patients with Established Cardiovascular Disease2024
  3. 3Remnant cholesterol and risk of coronary heart disease beyond LDL-cholesterol and HDL-cholesterol: a population-based prospective cohort study2025
  4. 4Triglyceride-Rich Lipoprotein Metabolism and Cardiovascular Risk in Diabetes: Bedside to Bench to Bedside2026 · 2 citations
  5. 5A Narrative Review of Remnant Cholesterol as an Independent Atherogenic Lipoprotein in Type 2 Diabetes: Pathophysiology and Clinical Implications2026