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October 10, 2025Jurnal Farmasi Sains dan PraktisOpen Access

Development of Labrasol®-Based Snedds for Enhanced Delivery of Combination Propolis, Sea Cucumber, and Centella Asiaticaextracts

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Authors

HFHannie FitrianiYSYandi SyukriMTMuhammad Taher

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Overview

This study demonstrates improved bioavailability of propolis, sea cucumber, and centella asiatica in a SNEDDS formulation, indicating potential therapeutic benefits.

Key Points

  • The optimized SNEDDS formulation exhibited nano-sized droplets, enhancing the delivery of the extracts.
  • Formulations showed a low PDI of 0.39 and a zeta potential of -50.30, indicating good stability.
  • SNEDDS formulations were assessed using droplet size and thermodynamic stability tests for effectiveness.
  • The combination of extracts displayed synergistic effects related to antioxidant and anti-inflammatory properties.

Cite This Study

Fitriani et al. (2025) studied this question.

synapsesocial.com/papers/68e861a57ef2f04ca37e47b2https://doi.org/10.31603/pharmacy.v11i3.14470
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