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October 10, 2025BMC Pulmonary MedicineOpen Access

A novel disulfidptosis-related mRNA signature predicts prognosis and therapeutic response in lung squamous cell carcinoma

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Authors

WBWei BaiNJNing JiangYDYuhan Deng

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Overview

This research identifies disulfidptosis-related genes' prognostic value in lung squamous cell carcinoma, suggesting new therapeutic targets.

Key Points

  • A novel 9-gene signature predicts survival outcomes in lung squamous cell carcinoma, highlighting prognostic value.
  • Analysis of transcriptomic data identified 9 disulfidptosis-related genes significantly associated with patient survival.
  • Multivariate Cox regression developed a risk score model that effectively stratifies patients based on prognosis.
  • Findings underline the clinical relevance of disulfidptosis and present potential biomarkers for therapeutic targeting.

Cite This Study

Bai et al. (2025) studied this question.

synapsesocial.com/papers/68e9435d2d5336d28fb289c2https://doi.org/10.1186/s12890-025-03920-6
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  1. 1Development of a disulfidptosis-related lncRNA prognostic signature for enhanced prognostic assessment and therapeutic strategies in lung squamous cell carcinoma2024 · 5 citations
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