Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 11, 2025Therapeutic Advances in GastroenterologyOpen Access

Comparative analysis of sporadic, IBD-associated, early-onset and late-onset colorectal cancer: a systematic review and meta-analysis

View Full Paper
Ask AI
Bookmark
Share

Authors

GFGiacomo FuschilloONOlga Maria NardoneGCGiulio Calabrese

Discussion

Loading...

Member takes

Overview

Systematic review and meta-analysis compare survival rates in colorectal cancer types, highlighting IBD-CRC's aggressive features.

Key Points

  • Overall survival was higher in sporadic colorectal cancer compared to inflammatory bowel disease-associated cancer.
  • Early-onset colorectal cancer exhibited longer survival than late-onset, with significant differences in diagnosis risk factors.
  • Patients with IBD-associated colorectal cancer had a younger average age at diagnosis and higher prevalence of mucinous tumours.
  • Inflammatory bowel disease-associated cancer was linked to shorter overall survival rates, indicating more aggressive disease characteristics.

Cite This Study

Fuschillo et al. (2025) studied this question.

synapsesocial.com/papers/68e9b1b5ba7d64b6fc132162https://doi.org/10.1177/17562848251379961
View Full Paper
Ask AI
Bookmark
Share