October 11, 2025CureusOpen Access

Cranial Neurolymphomatosis Presenting With Trigeminal Neuralgia and Facial and Vagus Nerve Palsies Visualized on Fluorodeoxyglucose Positron-Emission Tomography (FDG PET)

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Discussion

Case report reveals FDG PET findings in neurolymphomatosis linked to DLBCL, suggesting the need for vigilance.

Cranial neurolymphomatosis shows characteristic FDG PET imaging findings on relapse of non-Hodgkin lymphoma, emphasizing diagnostic potential.
A 68-year-old woman with DLBCL displayed neurological symptoms including trigeminal neuralgia and nerve palsies, revealing disease severity.
This observational analysis highlights the importance of FDG PET imaging for assessing neurolymphomatosis associated with lymphoma complications.
High clinical vigilance for neurolymphomatosis is essential, as early detection may significantly impact patient management and outcomes.

Tsoi et al. (2025) studied this question.

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