What type of study is this?

This is a Experimental Study study (also classified as: Animal Study).

October 11, 2025Tropical Journal of Pharmaceutical ResearchOpen Access

Hepatorenal protection of Justicia carnea leaf aqueous extract on sheep red blood cell-induced immunotoxicity in mice

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Authors

BIBenedict Bolakponumigha IwetanDelta State University GKGodfrey Rume KwekiDelta State University DODivine Avwerosuoghene OnobruduDelta State University

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Implication

Experimental evaluation shows Justicia carnea restores liver and kidney functions in mice with immunotoxicity induced by sheep red blood cells, indicating its potential as an adjuvant.

Key Points

Justicia carnea significantly improves liver and kidney functions in mice following SRBC-induced immunotoxicity.
Levels of AST, ALT, ALP, and ALB were significantly altered in SRBC mice, indicating liver stress with almost full recovery observed post-treatment.
Mice receiving 250 and 500 mg/kg of Justicia carnea had significantly increased total protein levels compared to control groups.
Aqueous extract treatment reduced SRBC-induced urea concentration, yet levels did not revert entirely to baseline, highlighting its protective impact.

Cite This Study

Iwetan et al. (2025) studied this question.

synapsesocial.com/papers/68e9b1d9ba7d64b6fc132fc0 https://doi.org/10.4314/tjpr.v24i5.5

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Implication

Experimental evaluation shows Justicia carnea restores liver and kidney functions in mice with immunotoxicity induced by sheep red blood cells, indicating its potential as an adjuvant.

Hepatorenal protection of Justicia carnea leaf aqueous extract on sheep red blood cell-induced immunotoxicity in mice

Discussion

Member takes

Implication

Key Points

Cite This Study

Hepatorenal protection of Justicia carnea leaf aqueous extract on sheep red blood cell-induced immunotoxicity in mice

Discussion

Member takes

Implication

Key Points

Cite This Study

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