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Clinical and biological predictors of treatment-free remission in CML

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This review identifies clinical and biological predictors of treatment-free remission in CML patients, highlighting their potential implications.

Approximately half of CML patients can achieve treatment-free remission after stopping TKIs, demonstrating significant results.
Key predictors for treatment-free remission include molecular response, disease features at diagnosis, and treatment history.
Advances in minimal residual disease assays enhance the ability to monitor remission status and predict outcomes in CML.
Understanding the immune environment and genomic profile is crucial for developing strategies to sustain treatment-free remission.

Sutton et al. (2025) studied this question.

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This review identifies clinical and biological predictors of treatment-free remission in CML patients, highlighting their potential implications.