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October 12, 2025Open Access

Unraveling Stage-Specific Metabolites in Human Milk and Their Links to Maternal Physiology: Insights from a Mexican Population

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Authors

IZImelda Cecilia Zarzoza-MendozaInstituto Nacional de Ciencias Médicas y Nutrición Salvador ZubiránMRMaricela Rodríguez‐CruzMexican Social Security InstituteMCMaría Cristina Carmona‐IsunzaUniversidad Nacional Autónoma de México

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Implication

Observational study characterizes metabolite variations in human milk across stages, highlighting maternal physiology connections.

Key Points

  • Distinct variations in human milk metabolite profiles reflect maternal characteristics and infant nutritional needs throughout lactation.
  • Analysis identified 23 metabolites, including amino acids, sugars, and fatty acids, with varying concentrations across lactation stages.
  • Prospective, longitudinal study evaluated human milk from 113 Mexican women practicing exclusive breastfeeding with advanced analytical techniques.
  • Positive correlations were found between several amino acids and maternal anthropometric variables, suggesting nutritional adaptations.

Cite This Study

Zarzoza-Mendoza et al. (2025) studied this question.

synapsesocial.com/papers/68ebc91af2c3e4d8d926e24fhttps://doi.org/10.20944/preprints202510.0555.v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Association Between Human Milk-Targeted Metabolites and Maternal Characteristics: Targeted Metabolomic Profiling of Human Milk in Low-Income Settings2026
  2. 2Characterization of Omics Components in Human Milk: A Systematic Review.2025
  3. 3NMR-Based Metabolomic Profiling Highlights Functional Nutritional Gaps Between Human Milk, Infant Formulas, and Animal Milks2025 · 7 citations
  4. 4Milk metabolites in relation with metabolomics: A perspective from scientometric analysis for trends and future2025 · 1 citations
  5. 5Milk metabolites in relation with metabolomics: A perspective from scientometric analysis for trends and future2025