What question did this study set out to answer?

This research aims to understand the relationship between the human milk metabolome and maternal and infant characteristics, especially in low-income contexts.

March 2, 2026Open Access

Association Between Human Milk-Targeted Metabolites and Maternal Characteristics: Targeted Metabolomic Profiling of Human Milk in Low-Income Settings

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Authors

SPSadia ParkarAga Khan University NMNadia MazharAga Khan University SSSumera SharafatAga Khan University

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Implication

Targeted metabolomic profiling shows associations between human milk metabolites and maternal characteristics in low-income settings, suggesting implications for infant nutrition.

Key Points

This research aims to understand the relationship between the human milk metabolome and maternal and infant characteristics, especially in low-income contexts.
Conducted targeted metabolomic profiling on 267 human milk samples.
Analyzed maternal and infant demographic data from participants in the MINE study.
Utilized the MxP® Quant 500 metabolomics kit for quantification of metabolites.
Identified 440 metabolites, primarily lipids like triglycerides and phosphatidylcholines.
Maternal age correlated positively with various metabolites, including cholesteryl esters and triglycerides.
Child age and gender also influenced specific metabolite profiles like ceramides and sphingomyelins.

Cite This Study

Parkar et al. (2026) studied this question.

synapsesocial.com/papers/69a52dd3f1e85e5c73bf0f08 https://doi.org/10.3390/metabo16030162

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Implication

Targeted metabolomic profiling shows associations between human milk metabolites and maternal characteristics in low-income settings, suggesting implications for infant nutrition.

Association Between Human Milk-Targeted Metabolites and Maternal Characteristics: Targeted Metabolomic Profiling of Human Milk in Low-Income Settings

Discussion

Member takes

Implication

Key Points

Cite This Study

Association Between Human Milk-Targeted Metabolites and Maternal Characteristics: Targeted Metabolomic Profiling of Human Milk in Low-Income Settings

Discussion

Member takes

Implication

Key Points

Cite This Study

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