What type of study is this?

This is a Cross-Sectional Study study (also classified as: Quantitative Study).

October 12, 2025PLoS ONEOpen Access

Identification and evaluation of potential microRNA markers for diagnostics in neurodegenerative diseases and correlation with other biochemical markers

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This analysis identifies potential microRNA biomarkers and their correlation with classical biochemical markers in neurodegenerative diseases.

The study identified hsa-miR-23a-3p and hsa-miR-29c-3p as promising microRNA biomarkers for neurodegenerative diseases, suggesting they could aid in diagnostics.
Significant correlations were found between selected microRNAs and classical biochemical markers like amyloid-β peptide 42, highlighting their diagnostic potential.
The analysis involved 126 patients categorized into five groups, including Alzheimer's and non-Alzheimer's dementia, determining the expression levels of microRNAs.
These findings support the potential use of specific microRNAs for future therapeutic applications and necessitate further robust studies.

Novobilský et al. (2025) studied this question.

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This analysis identifies potential microRNA biomarkers and their correlation with classical biochemical markers in neurodegenerative diseases.