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October 12, 2025Journal of Clinical MedicineOpen Access

Reconsidering Hormone Replacement Therapy: Current Insights on Utilisation in Premenopausal and Menopausal Women: An Overview

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Authors

VYVesselina YanachkovaMVMariela Vasileva‐SlavevaSKStoyan Kostov

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Overview

Overview reassesses hormone replacement therapy for menopausal symptoms, highlighting its clinical relevance and risks.

Key Points

  • Hormone replacement therapy effectively reduces menopausal symptoms, including vasomotor issues, and is crucial for osteoporosis prevention.
  • Current evidence indicates that HRT may carry risks for cardiovascular events and cancer, requiring thorough patient evaluation.
  • Careful consideration of a woman's age and health conditions is essential for deciding on hormone replacement therapy.
  • An individualized approach is paramount to balance the benefits and risks associated with hormone replacement therapy.

Cite This Study

Yanachkova et al. (2025) studied this question.

synapsesocial.com/papers/68ebffcfdef9fcb308ff23cchttps://doi.org/10.3390/jcm14207156
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hormone Replacement Therapy and Cardiovascular Risk in Postmenopausal Women2026 · 4 citations
  2. 2Menopausal Hormone Therapy: A Narrative Review of Contemporary Evidence2026 · 2 citations
  3. 3HORMONE REPLACEMENT THERAPIES IN MENOPAUSE2024
  4. 4A survey of hormone replacement therapy use among resistance-trained women across states of menopause transition – a preliminary analysis2025
  5. 5Hormone Replacement Therapy (HRT) Shortages for Treating Menopause: What Can Clinicians Do to Relieve Symptoms and Concerns?2024 · 4 citations