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October 12, 2025Open Access

Computational Fluid Dynamics Analysis of Coronary Stenosis: Hemodynamic and Geometric Determinants of Shear Stress Behavior on the Endothelial Wall

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Authors

MFMario Henrique Quim FerreiraVNValter Aragão do NascimentoJJJohannes Gérson Janzen

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Overview

Analysis demonstrates how coronary geometry and hemodynamics affect shear stress in arteries, suggesting risks for plaque rupture.

Key Points

  • Higher blood viscosity and density from increased hematocrit raised shear stress levels significantly, impacting plaque health.
  • CFD simulations indicated that geometric variations in arterial structure caused substantial changes in shear stress distribution on the endothelial wall.
  • Stenosis locations and arterial tapering altered shear stress patterns, challenging traditional measures of ischemic risk assessment.
  • WSS values reaching over 30 Pa highlight the critical role of geometric and hemodynamic factors in cardiovascular health management.

Cite This Study

Ferreira et al. (2025) studied this question.

synapsesocial.com/papers/68ebffcfdef9fcb308ff2481https://doi.org/10.20944/preprints202510.0781.v1
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