Why the study?
Do simulated plaques causing ≥60% stenosis alter hemodynamic parameters in left coronary artery models?
Population
Simulated left coronary artery models generated from a single sample patient's data
Comparison
Simulated plaques placed at the left main stem… vs Left coronary models without the presence of…
Design
Preclinical
Authors
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Hypothesis-generating in animal CFD models; human validation required before any clinical consideration of stenosis hemodynamics.
Do simulated plaques causing ≥60% stenosis alter hemodynamic parameters in left coronary artery models?
Computational fluid dynamics simulation demonstrates a direct correlation between coronary plaques causing ≥60% stenosis and significant hemodynamic changes such as increased pressure gradients and altered flow velocities.
Chaichana et al. (2012) studied this question.
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