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October 13, 2025Open Access

Hybrids reveal accessible chromatin trans genetic associations

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Authors

MMMark A.A. MinowUniversity of GeorgiaAMAlexandre P. MarandUniversity of MichiganXZXuan ZhangUniversity of Pisa

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Implication

Analysis shows that chromatin accessibility affects gene expression in hybrid maize, suggesting new genetic insights.

Key Points

  • Hybrid maize exhibits heterosis, showing increased growth and yield due to genetic factors and chromatin changes.
  • Using ATAC-seq, chromatin accessibility inheritance patterns were uncovered, with dominant traits identified in specific crosses.
  • The study highlights the role of trans-regulatory variants in influencing gene expression and hybrid performance.
  • Innovative discovery methods enable better understanding of genetic interactions, potentially enhancing advancements in maize breeding.

Cite This Study

Minow et al. (2025) studied this question.

synapsesocial.com/papers/68ec51df42911f61ef8b2039https://doi.org/10.1101/2025.10.09.681407
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Chromatin accessibility landscape and its association with heterosis in maize hybrids2026 · 1 citations
  2. 2Genome‐wide chromatin accessibility reveals transcriptional regulation of heterosis in inter‐subspecific hybrid rice2024 · 20 citations
  3. 3Accessible chromatin regions and DNA methylation regulate gene expression leading to changes in agronomic traits in Brassica allotriploid hybrids2024
  4. 4The incomplete dominance of gene expression controlled by Trans-eQTL hotspots contributes to heterosis in maize2026 · 2 citations
  5. 5Integrating Dynamic 3D Chromatin Architecture and Gene Expression Alterations Reveal Heterosis in Brassica rapa2024 · 3 citations