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October 13, 2025MedCommOpen Access

Immune Surveillance and Immune Escape in Cancer: Mechanisms and Immunotherapy

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Authors

YPYing PengLZLinsheng ZhanJSJianxiang Shi

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Overview

This review highlights immune escape mechanisms and T cell involvement in cancer, suggesting refinements for current immunotherapies.

Key Points

  • Effective cancer immunity relies on intricate interactions between tumor cells and immune sentinels, improving treatment outcomes.
  • Both tumor intrinsic and tumor microenvironmental factors are crucial in understanding immune escapes during cancer therapies.
  • Analysis centers on T cells, notably effector and helper subsets, alongside antigen presentation cells, highlighting their immune roles.
  • Insights gained could lead to refined immunotherapy strategies, promoting effective anticancer immune responses.

Cite This Study

Peng et al. (2025) studied this question.

synapsesocial.com/papers/68ec51e642911f61ef8b2510https://doi.org/10.1002/mco2.70321
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