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October 15, 2025Bali Journal of AnesthesiologyOpen Access

Comparative Evaluation of Intrathecal Nalbuphine as an Adjuvant to Bupivacaine in Elective Cesarean Sections: A Randomized, Double-blind, Controlled Trial

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Authors

SDSittiporn DeetayartRatchaburi HospitalWTWeerawat ThangthumBoromarajonani College of Nursing

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Overview

Randomized trial compares nalbuphine doses in elective cesarean sections, indicating improved pain relief.

Key Points

  • Intrathecal nalbuphine significantly enhances postoperative analgesia duration compared to control.
  • Groups receiving nalbuphine had prolonged analgesia, particularly the 2.0 mg dose, with low adverse effects.
  • Randomized, double-blind controlled trial included 120 parturients undergoing elective cesarean sections.
  • Intrathecal nalbuphine offers effective pain management, suggesting a promising opioid adjuvant in anesthesia.

Cite This Study

Deetayart et al. (2025) studied this question.

synapsesocial.com/papers/68efa18f9d05deea71d13ddbhttps://doi.org/10.4103/bjoa.bjoa_150_25
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Analgesic Effect of Intrathecal Nalbuphine versus Intrathecal Fentanyl as Adjuvant to 0.5% Bupivacaine for Cesarian Section under Spinal Anaesthesia2024
  2. 2Assessment of the Efficacy of Nalbuphine as an Adjuvant to Intrathecal Bupivacaine in Endoscopic Urological Surgeries for the Prolongation of Postoperative Analgesia2024
  3. 3A comparative study on the effect of intrathecal nalbuphine and buprenorphine as an adjuvant to 0.5% hyperbaric bupivacaine in elective infraumbilical surgeries2024 · 3 citations
  4. 4Comparative Study to Assess Efficacy of Nalbuphine vs Fentanyl as an Adjuvant to Intrathecal 0.5% Hyperbaric Bupivacaine for Lower Abdominal Surgeries: A Randomized Control Trial2023
  5. 5Comparison of nalbuphine and morphine as intrathecal adjuvant to 0.5% bupivacaine for post-operative analgesia in lower abdominal surgeries – A randomized and control study2024