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October 15, 2025

Cisplatin-induced Genotoxicity and Protective Effect of Aqueous Ginkgo Biloba Extract in an Animal Model

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Authors

MAMushtaq Talib Al-Safi

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Overview

Animal model reveals ginkgo biloba extract reduces cisplatin-induced genotoxicity and sperm abnormalities.

Key Points

  • Ginkgo biloba extract significantly reduced cisplatin-induced micronuclei in male mice.
  • Treatment with ginkgo biloba at 50, 100, and 150 mg/kg showed decreasing sperm abnormalities.
  • Cisplatin alone caused significant genotoxic effects, while combined treatment showed protective benefits.
  • Micronucleus and sperm abnormality tests confirmed the protective role of ginkgo biloba extract.

Cite This Study

Mushtaq Talib Al-Safi (2025) studied this question.

synapsesocial.com/papers/68efd921056559ef42877706https://doi.org/10.21070/ijhsm.v2i1.145
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