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This is a Pre-Registered Trial study (also classified as: Experimental Study).

Orally administered cholestyramine increases fecal bile acid excretion in healthy dogs

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This experimental study shows cholestyramine improves fecal bile acid levels in healthy dogs, indicating potential for treating BA diarrhea.

Cholestyramine significantly increased total fecal bile acids in dogs after treatment, leading to improved bile acid excretion.
12 dogs completed the study, with no adverse events reported during cholestyramine administration.
Use of repeated-measures ANOVAs revealed significant improvements in fecal bile acid levels at multiple time points after treatment.
These results support further investigation of cholestyramine in dogs with suspected bile acid diarrhea.

Tolbert et al. (2025) studied this question.

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This experimental study shows cholestyramine improves fecal bile acid levels in healthy dogs, indicating potential for treating BA diarrhea.