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October 15, 2025Artificial OrgansOpen Access

Vasoreactivity as a Measure of Kidney Viability During Ex Vivo Normothermic Machine Perfusion

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This analysis shows how warm ischemic injury affects renal responses in porcine kidneys, indicating potential viability markers for transplant.

Prolonged warm ischemia significantly impairs renal vascular response and compromise function during perfusion.
After dopamine infusion, renal blood flow significantly increased, with notable differences between 30 and 60 min warm ischemia.
Observational study involving fourteen porcine kidneys, demonstrating effects of warm ischemia on renal vascular function.
Findings highlight that renal vascular responses to vasoactive drugs could quantify ischemic damage and assess kidney viability.

Tricht et al. (2025) studied this question.

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This analysis shows how warm ischemic injury affects renal responses in porcine kidneys, indicating potential viability markers for transplant.