What type of study is this?

October 16, 2025PeerJOpen Access

Identification of diabetes related phenotype and diagnostic biomarkers in coronary artery disease

View Full Paper

Ask AI

Bookmark

Authors

Analysis reveals 16 diabetes-related genes in coronary artery disease, suggesting novel diagnostic biomarkers.

The study identifies a diagnostic model for coronary artery disease with an AUC of 0.8, indicating high reliability.
Phenotype 1 in CAD patients exhibited higher levels of cytokines and increased immune cell infiltration compared to phenotype 2.
LASSO regression analysis successfully highlighted 16 diabetes-related genes applicable as biomarkers for CAD diagnostics.
Mouse model experiments validated high expression of KCNQ1 and ITPK1 in macrophages, implicating their role in myocardial injury.

Aihemaiti et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark